Topical and Systemic Formulation Options for Cutaneous T Cell Lymphomas
نویسندگان
چکیده
منابع مشابه
Primary cutaneous T-cell lymphomas.
Primary cutaneous T-cell lymphomas (CTCLs) encompass a clinically and biologically heterogeneous group of non-Hodgkin lymphomas (NHLs) defined by clonal proliferation of skin-homing malignant T lymphocytes and natural killer cells. They account for up to 75% to 80% of all cutaneous lymphomas. The current WHO-EORTC classification of cutaneous lymphomas with primary cutaneous manifestations lists...
متن کاملGenotypic analysis of cutaneous T-cell lymphomas.
The gene encoding the beta-chain of the T-cell antigen receptor (TCR) has been analyzed for evidence of rearrangement in skin, blood, and lymph node specimens from 23 cases of known or suspected cutaneous T-cell lymphoma (CTCL). Two cutaneous large cell lymphomas, 4 cases of Sézary syndrome, and 5 cases of advanced (tumor) stages of mycosis fungoides showed clonal rearrangement of the TCR beta-...
متن کامل[Eczema herpeticum in cutaneous T-cell lymphomas].
1. Bardach H. Perforating lichen nitidus. J Cutan Pathol. 1981;8:111-6. 232-6. 2. Banse-Kupin L, Morales A, Kleinsmith DA. Perforating lichen nitidus. J Am Acad Dermatol. 1983;9:452-6. 3. Itami A, Ando I, Kukita A. Perforating lichen nitidus. Int J Dermatol. 1994;33:382-4. 4. Yoon TY, Kim JW, Kim MK. Two cases of perforating lichen nitidus. J Dermatol. 2006;33:278-80. 5. Rudd ME, Ha T, Schofiel...
متن کاملAn overview of cutaneous T cell lymphomas
Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of extranodal non-Hodgkin's lymphomas that are characterized by a cutaneous infiltration of malignant monoclonal T lymphocytes. They typically afflict adults with a median age of 55 to 60 years, and the annual incidence is about 0.5 per 100,000. Mycosis fungoides, Sézary syndrome, and primary cutaneous peripheral T cell lymphomas not ...
متن کاملPLCG1 mutations in cutaneous T-cell lymphomas.
Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of primary cutaneous T-cell lymphoproliferative processes, mainly composed of mycosis fungoides and Sézary syndrome, the aggressive forms of which lack an effective treatment. The molecular pathogenesis of CTCL is largely unknown, although neoplastic cells show increased signaling from T-cell receptors (TCRs). DNAs from 11 patients with ...
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ژورنال
عنوان ژورنال: Pharmaceutics
سال: 2021
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics13020200